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Bottom line: Choose Tirzepatide if you want the largest expected weight-loss response and stronger glucose improvementsespecially for prediabetes/T2D and recomposition goals (with structured training and nutrition)

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Early research on injectable semaglutide is promising

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Prioritizing Safety and Counseling for GLP-1 in Pregnancy Current international guidelines advise against initiating or continuing GLP-1 RAs during pregnancy due to limited human safety data